Botulinum Toxin Type A: Brands

With botulinum toxins, there are several brands to choose from. I often get asked “Which brand is better?” and it is all dependent on the person.

Some brands seem to work better on specific individuals, so I recommend trying them out to see where your preference lies. The main difference in these products is their purification manufacturing processes – some items contain accessory proteins and/or albumin. They are all working towards the same end goal.

  • Botox (onabotulinumtoxinA)

FDA Approved: 2002

Prepared using a complex purification process which results in a complex containing toxins and other proteins which is then freeze-dried and sealed.

  • Dysport (abobotulinumtoxinA)

FDA Approved: 2009

Prepared using purification techniques which is then freeze-dried and sealed.

  • Xeomin (incobotulinumtoxinA)

FDA Approved: 2011

Prepared using extensive purification process XTRACT which removes complex proteins and contains only active components which are then freeze-dried and sealed.

  • Jeuveau (prabotulinumtoxinA)

FDA Approved: 2019

Prepared using Hi-Pure technology purification process to obtain >95% pure components which is then freeze-dried and sealed.

  • Daxxify (daxibotulinumtoxinA)

FDA Approved: 2022

First peptide-formulated, long-acting botulinum toxin; median duration of 6 months.

Peptide aids in both the stability and delivery of toxin. No accessory proteins, no albumin, no animal derivates.

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Cosmetic Uses of Neurotoxins

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Neurotoxins: What are they & how do they work?